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Home >> Antibodies >> CD50 / ICAM3

CD50 / ICAM3

Mouse Monoclonal Antibody [Clone ICO-60]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

ICAMR; Intercellular adhesion molecule 3 (ICAM3)

Positive Control

HL-60 or THP-1 cells. Lymph node and tonsil.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human ICAM3

Cellular Localization

Cell surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

110-160kDa

Specificity & Comments

Recognizes the N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Baryshnikov A. et al., Gemat.Trasf. (Russian) N8, 4-7, (1990)
  2. Baryshnikov A, and Tonevitsky A, Monoclonal antibodies in laboratory and clinic. Thesis p212, (1997).
  3. Martinova T.et al., In: Problems in medical biotechnology and immunological infections diseases. Vol 11, 182-186 (1996).
  4. Leukocyte typing V, Schlossman et al., Oxford Univ. Press, 1546 and 1583 (1993).

Bioinformatics

  •  Entrez Gene ID: 3385
  •  Gene Symbol: ICAM3
  •  SwissProt: P32942
  •  Chromosome Location: 19p13.2
  •  Unigene: 354563
NBT01040