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Home >> Antibodies >> CD3e, Mouse

CD3e, Mouse

Hamster Monoclonal Antibody [Clone 145-2C11]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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SDS-PAGE Analysis Purified CD3e Hamster Monoclonal Antibody (145-2C11).

Product Details

Synonyms

CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex); IMD18; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE

Positive Control

MPBMC's or Thymus or Lymph Node.

Known Applications & Suggested Dilutions

Func., Flow Cyt, IF         More Details

Functional Studies (Order Antibody without BSA & Azide)
Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37

Cellular Localization

Cell Surface

Species Reactivity

Mouse. Does not react with Human.

Host / Ig Isotype

Armenian Hamster / IgG, kappa

Mol. Weight of Antigen

23kDa

Specificity & Comments

CD3 chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful forin vitroblocking and activation assays, as well as apoptosis induction andin vivoT cell depletion.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activation)
  2. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  3. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  4. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  5. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  6. Wang W, et al. 2007. J. Immunol. 178:4885. (Activation)
  7. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)

Bioinformatics

  •  Entrez Gene ID: 12501
  •  Gene Symbol: Cd3e (Mouse)
  •  SwissProt: P22646
  •  Chromosome Location: 9 A5.2; 9 24.84 cM (Mouse)
  •  Unigene: 210361
NBT02013