2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CD100 (Semaphorin-4D)

CD100 (Semaphorin-4D)

Mouse Monoclonal Antibody [Clone SEMA4D/933]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

COLL4; Collapsin4; GR3; M sema G; MSEMA; SEMA4D; Semacl2; SemaH; SEMAJ; Semaphorin C like 2; Semaphorin H; Semaphorin J; Semaphorin-4D; Semcl2

Positive Control

Daudi, Raji, HUT-78, Kg1a, U937 and human lymphocytes. Human tonsils and lymph nodes.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human recombinant SEMA4D protein

Cellular Localization

Cell surface

Species Reactivity

Human. Non-Human primates.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

50kDa (Monomer)

Specificity & Comments

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Schlossman SL Bloumsell W Gilks et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press New York.
  2. Knapp WB Dorken EP. Rieber et al, eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press New York.

Bioinformatics

  •  Entrez Gene ID: 10507
  •  Gene Symbol: SEMA4D
  •  SwissProt: Q92854
  •  Chromosome Location: 9q22.2
  •  Unigene: 494406
NBT00933