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Home >> Antibodies >> Aromatase / Cytochrome P450 (CYP19A1)

Aromatase / Cytochrome P450 (CYP19A1)

Mouse Monoclonal Antibody [Clone CYP19A1/4257]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified Aromatase / CYP450 Mouse Monoclonal Antibody (CYP19A1/4257). Confirmation of Integrity and Purity of Antibody.

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Formalin-fixed, paraffin-embedded human placenta stained with Aromatase / CYP450 Mouse Monoclonal Antibody (CYP19A1/4257).

Product Details

Synonyms

CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19

Positive Control

Human normal placenta.

Known Applications & Suggested Dilutions

ELISA, Western Blot, IHC-P         More Details

ELISA (For coating, order antibody without BSA)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide corresponding to aa376-390 of human aromatase (KALEDDVIGYPVKK)

Cellular Localization

Membrane

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a

Mol. Weight of Antigen

55kDa

Specificity & Comments

CYP450 Aromatase is part of the CYP19A1 family involved in the aromatization of androgens to estrogens, a highly conserved mechanism amongst mammals. Clone CYP19A1/4257 recognizes a conserved epitope on the CYP450 aromatase, allowing for detection of aromatase levels using various analysis methods.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Turner, KJ, et al. (2002) Development and Validation of a New Monoclonal Antibody to Mammalian Aromatase. Journal of Endocrinology.

Bioinformatics

  •  Entrez Gene ID: 1588
  •  Gene Symbol: CYP19A1
  •  SwissProt: O14793
  •  Chromosome Location: 2q32.2
  •  Unigene: 41565