2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Apolipoprotein A4 / apoA-IV

Apolipoprotein A4 / apoA-IV

Mouse Monoclonal Antibody [Clone APOA4/3372]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human liver stained with Apolipoprotein A4 Mouse Monoclonal Antibody (APOA4/3372).

img

Formalin-fixed, paraffin-embedded human liver carcinoma stained with Apolipoprotein A4 Mouse Monoclonal Antibody (APOA4/3372).

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using Apolipoprotein A4 Mouse Monoclonal Antibody (APOA4/3372).

Product Details

Synonyms

ApoA4; Apolipoprotein A-IV

Positive Control

Human ovarian cancer and cervical cancer tissues.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Human recombinant APOA4 protein fragment (around aa 239-371) (exact sequence is proprietary)

Cellular Localization

Secreted.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

46kDa

Specificity & Comments

Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Chistiakov DA et al. Lab Invest. 2016 Jul;96(7):708-18.

Bioinformatics

  •  Entrez Gene ID: 337
  •  Gene Symbol: APOA4
  •  SwissProt: P06727
  •  Chromosome Location: 11q23.3
  •  Unigene: 1247
NBT03372