|Catalog No||Formulation||Size||Price (USD)|
|7531-MSM1-P0||Purified Ab with BSA and Azide at 200ug/ml||20 ug||199.00|
|7531-MSM1-P1||Purified Ab with BSA and Azide at 200ug/ml||100 ug||429.00|
|7531-MSM1-P1ABX||Purified Ab WITHOUT BSA and Azide at 1.0mg/ml||100 ug||429.00|
|Human Entrez Gene ID||7531|
|Human Gene Symbol||YWHAE|
|Human Chromosome Location||17p13.3|
|Synonyms||MDS; epididymis luminal protein 2; mitochondrial import stimulation factor (MSF) L subunit; Mitochondrial import stimulation factor L subunit; MSF L; protein kinase C inhibitor protein-1|
|Immunogen||Recombinant human full-length YWHAE protein|
|Host / Ig Isotype||Mouse / IgG2a, kappa|
|Mol. Weight of Antigen||29.4kDa|
|Cellular Localization||Cytoplasm. Melanosome.|
|Species Reactivity||Human. Others-not tested.|
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
Western Blotting (0.5-1.0ug/ml)
Optimal dilution for a specific application should be determined.
HEK-293 or A-431 cell lines.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
This antibody is available for research use only and is not approved for use in diagnosis.
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.