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Recombinant ER-beta-1 (Estrogen Receptor beta-1) Antibody [ESR2/13819R]

In Stock
Catalog Number Formulation Size Price
2100-RBM23-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2100-RBM23-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2100-RBM23-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560)., Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Nucleus
Gene Name
ESR2
Positive Control
Expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus
Immunogen
Recombinant fragment (around aa515-530) of the human Estrogen Receptor beta 1 protein (exact sequence is proprietary)
Alternate Names
Estrogen receptor beta, ER-BETA|ESR-BETA|ESRB|ESTRB|Erb|NR3A2|ODG8

Database Links

Entrez Gene ID
2100
SwissProt
Q92731

Additional Information

Clone
ESR2/13819R
Chromosome Location
14q23.2-q23.3
Mol. Weight of Antigen
59.22kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All ESR2 Antibodies

Functions

  • Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560)., Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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