VEGF-R2 / CD309 / Flk-1 / KDR3 [DC101]



This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

Product Properties & Targets

Species Reactivity
Gene Name
Mol. Weight of Antigen
Recombinant full-length Mouse VEGFR2 protein

Database Links

Entrez Gene ID

Additional Information

Human Gene Symbol
Kdr (Mouse)
Chromosome Location
5 C3.3; 5 40.23 cM (Mouse)

Known Applications & Suggested Dilutions

  • Western Blot (Non-reducing) (2-5ug/ml)
  • Blocks Binding of VEGF to VEGF-R2 (Order Ab without BSA & Azide)
  • Inhibits VEGF-induced Signaling (Order Ab without BSA & Azide)
  • Blocks Tumor Growth in mice (Order Ab without BSA & Azide)
  • Neutralizing
  • Optimal dilution for a specific application should be determined.

Key References

  • Witte L, et al. Cancer Metastasis Rev. 1998 Jun;17(2):155-61.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.


This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.


There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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