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RBMS2 / SCR3 Antibody [PCRP-RBMS2-1B6]

In Stock
HuProt Validated
Catalog Number Formulation Size Price
5939-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
5939-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
5939-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells

Summary

RBMS2 is a member of a small family of proteins that bind single stranded DNA or RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, and are required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. RBMS2 (RNA-binding motif, single-stranded-interacting protein 2) is a 407 amino acid protein that contains 2 RRM (RNA recognition motif) domains and localizes to nucleus. It has been suggested that RBMS2 suppresses Cdc2 kinase and Cdc13 cyclin mutants through the induction of translation of Cdc2. The RBMS2 gene is conserved in chimpanzee, canine, bovine, mouse, rat and zebrafish, and maps to human chromosome 12q13.3.

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Research Areas
Isotype / Light Chain
IgG1 /
Cellular Localization
Nucleus
Gene Name
Positive Control
Nuclear and cytoplasmic expression in all tissues.
Immunogen
Recombinant full-length human RBMS2 protein
Alternate Names
RNA-binding motif, single-stranded-interacting protein 2, Suppressor of CDC2 with RNA-binding motif 3, RNA binding motif, single stranded interacting protein 2; Suppressor of CDC2 with RNA-binding motif 3 (SCR3)

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-RBMS2-1B6
Chromosome Location
12q13.13
Mol. Weight of Antigen
43.95kDa

Key References

  • Blackshaw S, et al. A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Nature methods 15.5 (2018 May): 330-338.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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