Formalin-fixed, paraffin-embedded human pituitary stained with Prolactin Recombinant Rabbit Monoclonal Antibody (PRL/4906R).

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using PRL/4906R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human pituitary stained with Prolactin Recombinant Rabbit Monoclonal Antibody (PRL/4906R).

Prolactin (Pituitary Tumor Marker) [PRL/4906R]

Name: Prolactin (Pituitary Tumor Marker)
SKU: 5617-RBM6
Availability: InStock

Monoclonals Primary Antibodies Rabbit Monoclonals Recombinant Rabbit Monoclonals Recombinants

Summary

Prolactin is a growth factor that is secreted by the anterior pituitary. It is necessary for the proliferation and differentiation of the mammary glands. Prolactin is useful in the classification of pituitary tumors and study of pituitary disease. It also plays a role in the development of mammary cancer, functioning dually as a mitogen and a differentiating agent.

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Product Properties & Targets

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Cellular Localization

Secreted

Gene Name

PRL

Mol. Weight of Antigen

27kDa

Immunogen

Recombinant fragment of human Prolactin (PRL) protein (around aa 63-201) (exact sequence is proprietary)

Database Links

Entrez Gene ID

5617

Unigene

1905

SwissProt

IDP01236

Additional Information

Clone

PRL/4906R

Human Gene Symbol

PRL

Chromosome Location

6p22.3

Known Applications & Suggested Dilutions

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Key References

Goffin, V., et al. 1998. Prolactin: a hormone at the crossroads of neuroimmunoendocrinology. Ann. N.Y. Acad. Sci. 840: 498-509.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.