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Recombinant Prolactin (Pituitary Tumor Marker) Antibody [PRL/4906R]

In Stock
Catalog Number Formulation Size Price
5617-RBM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
5617-RBM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
5617-RBM6-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant Prolactin (Pituitary Tumor Marker) Antibody

Formalin-fixed, paraffin-embedded human pituitary stained with Prolactin Recombinant Rabbit Monoclonal Antibody (PRL/4906R).

Recombinant Prolactin (Pituitary Tumor Marker) Antibody - Image 2

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using PRL/4906R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Recombinant Prolactin (Pituitary Tumor Marker) Antibody - Image 3

Formalin-fixed, paraffin-embedded human pituitary stained with Prolactin Recombinant Rabbit Monoclonal Antibody (PRL/4906R).

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Prolactin is a growth factor that is secreted by the anterior pituitary. It is necessary for the proliferation and differentiation of the mammary glands. Prolactin is useful in the classification of pituitary tumors and study of pituitary disease. It also plays a role in the development of mammary cancer, functioning dually as a mitogen and a differentiating agent.

Product Properties & Targets

Antibody Type
Rabbit Monoclonals, Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Research Areas
Immunology, Cytokine Signaling
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Secreted
Gene Name
PRL
Positive Control
Pituitary tissue. Pituitary lysate.
Immunogen
Recombinant fragment of human Prolactin (PRL) protein (around aa 63-201) (exact sequence is proprietary)
Alternate Names
Prolactin, Decidual prolactin; GHA1; Growth hormone A1; Lactogenic hormone; Luteotropic hormone; Mammotropin; PRL; Prolactin; Prolactin precursor

Database Links

Entrez Gene ID
5617
SwissProt
IDP01236

Additional Information

Clone
PRL/4906R
Chromosome Location
6p22.3
Mol. Weight of Antigen
27kDa

Related Antibodies

View All PRL Antibodies

Functions

  • Prolactin acts primarily on the mammary gland by promoting lactation.

Key References

  • Goffin, V., et al. 1998. Prolactin: a hormone at the crossroads of neuroimmunoendocrinology. Ann. N.Y. Acad. Sci. 840: 498-509.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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