
SDS-PAGE Analysis of Purified BATF2 Mouse Monoclonal Antibody (PCRP-BATF2-2B9). Confirmation of Purity and Integrity of Antibody.

Flow cytometric analysis of PFA-fixed HeLa cells. BATF2 Mouse Monoclonal Antibody (PCRP-BATF2-2B9) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with BATF2 Mouse Monoclonal Antibody (PCRP-BATF2-2B9). Inset: PBS instead of primary antibody; secondary only negative control.

Analysis of Protein Array containing more than 19,000 full-length human proteins using BATF2 Mouse Monoclonal Antibody (PCRP-BATF2-2B9). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in defense response to protozoan; myeloid dendritic cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. This antibody recognizes a transcription factor involved in differentiation of CD8+ thymic dendritic cells. BATF2 has been implicated in breast cancer, malignant glioma and metastatis melanoma progression.
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