Home >> Antibodies >> Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)

Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)

Recombinant Mouse Monoclonal Antibody [Clone rPODXL/2184]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Product Details

Synonyms

PODXL, PDXL, GCTM-2; Gp200; PCLP1; Pcx; Podocalyxin-like protein 1

Positive Control

HeLa, Raji or Jurkat cells. Human angiosarcoma or kidney tissue.

Known Applications & Suggested Dilutions

ELISA More Details

ELISA (For coating, order antibody without BSA)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Cellular Localization

Cell Surface and Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

165-170kDa

Specificity & Comments

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.