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Home >> Antibodies >> HLA-DP (MHC II)

HLA-DP (MHC II)

Mouse Monoclonal Antibody [Clone BRA-FB6]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified HLA-DP Mouse Monoclonal Antibody (BRA-FB6). Confirmation of Integrity and Purity of Antibody.

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Flow Cytometric Analysis of PFA-fixed Raji cells. HLA-DP Mouse Monoclonal Antibody (BRA-FB6) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).

Product Details

Synonyms

HLA class II histocompatibility antigen DP alpha 1 chain; HLA DP1A; HLA SB alpha chain; HLADP; HLADPA1; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; Major histocompatibility complex class II DP alpha 1; MHC class II DP3 alpha; MHC class II DPA1; PLT1; Primed lymphocyte test 1

Positive Control

Raji cells. Tonsil or lymph node.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, IF         More Details

ELISA (For coating use Ab at 2-4ug/ml, order Ab without BSA)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Non-T, non-B human acute lymphoblastic leukemia REH6 cell line

Cellular Localization

Cell surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

33-35kDa

Specificity & Comments

Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35kDa) and beta (27-30kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Babusikova O., et al. Neoplasma, 1985, 32(6):657-62.
  2. Horejsi V, et. al. Tissue Antigens, 1988, 32(1):6-11.
  3. Polakova K., et al. Neoplasma, 1985, 32(6):641-8.
  4. Neoplasma 34(4), 417- 425, (1987).

Bioinformatics

  •  Entrez Gene ID: 3115
  •  Gene Symbol: HLA-DPB1
  •  SwissProt: P04440
  •  Chromosome Location: 6p21.3
  •  Unigene: 347270
NBT00199