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Home >> Antibodies >> HGF / SF

HGF / SF

Mouse Monoclonal Antibody [Clone EGH2 4C12.1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00

Product Details

Synonyms

F-TCF; Fibroblast derived tumor cytotoxic factor; Hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor beta chain; Hepatopoietin-A; HGF; HGFB; HPTA; Lung fibroblast derived mitogen; Scatter Factor

Positive Control

HGF lysate.

Known Applications & Suggested Dilutions

ELISA         More Details

ELISA (For coating, order antibody without BSA)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human HGF/SF protein.

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

91/64/34kDa precursor//

Specificity & Comments

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Miyazawa, K., et al. 1994. J. Biol. Chem. 269: 8966-8970.

Bioinformatics

  •  Entrez Gene ID: 3082
  •  Gene Symbol: HGF
  •  SwissProt: P14210
  •  Chromosome Location: 7q21.11
  •  Unigene: 396530, 561679
NBT02841