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Home >> Antibodies >> GDF9 (Growth Differentiation Factor 9)

GDF9 (Growth Differentiation Factor 9)

Rat Monoclonal Antibody [Clone GDF9/4262]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified GDF9 Rat Monoclonal Antibody (GDF9/4262) Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

Growth/differentiation factor 9, GDF-9, GDF9

Positive Control

Human ovary.

Known Applications & Suggested Dilutions

ELISA, Western Blot         More Details

ELISA (For coating, order antibody without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

N-terminal of GDF9, corresponding to sequence KKPLGPASFNLSEYFC.

Cellular Localization

Cytoplasmic (secreted)

Species Reactivity

Human.

Host / Ig Isotype

Rat / IgG1

Mol. Weight of Antigen

51kDa

Specificity & Comments

GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/4262 can be used in assays to detect GDF9 expression and help diagnose ovarian disorders.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Gilchrist, R.B., et al. (2004) Immunoneutralization of Growth Differentiation Factor 9 Reveals It Partially Accounts for Mouse Oocyte Mitogenic Activity. Biol Reprod; 71 (3): 732-739.

Bioinformatics

  •  Entrez Gene ID: 2661
  •  Gene Symbol: GDF9
  •  SwissProt: O60383
  •  Chromosome Location: 5q31.1
  •  Unigene: 25022