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Home >> Antibodies >> Fos-related antigen 2 (FRA-2) / FOS-like antigen 2 (FOSL2)

Fos-related antigen 2 (FRA-2) / FOS-like antigen 2 (FOSL2)

Mouse Monoclonal Antibody [Clone PCRP-FOSL2-1B1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Immunofluorescence Analysis of PFA-fixed HeLa cells using FOSL2 Mouse Monoclonal Antibody (PCRP-FOSL2-1B1) followed by goat anti-mouse IgG-CF488 (green). Counterstain is phalloidin.

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Flow cytometric analysis of PFA-fixed HeLa cells. FOSL2 Mouse Monoclonal Antibody (PCRP-FOSL2-1B1) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).

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SDS-PAGE Analysis Purified FOSL2 Mouse Monoclonal Antibody (PCRP-FOSL2-1B1). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FOSL2 Mouse Monoclonal Antibody (PCRP-FOSL2-1B1).

Product Details

Synonyms

FLJ23306; FOS like antigen 2; Fos-related antigen 2 (FRA-2); Fosl2

Positive Control

HeLa, MCF7 or 293T cells.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human FOSL2 protein

Cellular Localization

Nucleus.

Species Reactivity

Human

Host / Ig Isotype

Mouse / IgG1

Mol. Weight of Antigen

40kDa

Specificity & Comments

The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Blackshaw S., et al. Nature methods 15.5 (2018 May): 330-338.
  2. Sambucetti, L.C., et al. 1986. Science 234: 1417-1419.

Bioinformatics