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Home >> Antibodies >> Fatty Acid Binding Protein (Liver) / FABP1

Fatty Acid Binding Protein (Liver) / FABP1

Mouse Monoclonal Antibody [Clone FABP1/3486]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Formalin-fixed, paraffin-embedded human kidney stained with FABP1 Mouse Monoclonal Antibody (FABP1/3486).

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Formalin-fixed, paraffin-embedded human kidney stained with FABP1 Mouse Monoclonal Antibody (FABP1/3486).

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SDS-PAGE Analysis Purified FABP1 Mouse Monoclonal Antibody (FABP1/3486). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FABP1 Mouse Monoclonal Antibody (FABP1/3486).

Product Details

Synonyms

FABP1, L-FABP

Positive Control

Liver or colon carcinoma tissues (IHC).

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)

Cellular Localization

Cytoplasm. Nuclear.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

14kDa

Specificity & Comments

Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Kaikaus, R.M., et al. 1993. Mechanisms of regulation of liver fatty acid binding protein. Mol. Cell. Biochem. 123: 93-100.

Bioinformatics

  •  Entrez Gene ID: 2168
  •  Gene Symbol: FABP1
  •  SwissProt: P07148
  •  Chromosome Location: 2p11.2
  •  Unigene: 380135
NBT03486