2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> EBV Early Antigens (Epstein Barr Virus)

EBV Early Antigens (Epstein Barr Virus)

Mouse Monoclonal Antibody [Clone 1108-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

SDS-PAGE Analysis Purified EBV Mouse Monoclonal Antibody (1108-1). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4)

Positive Control

EBV-infected cells. Tissues.

Known Applications & Suggested Dilutions

IF         More Details

Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Affinity Purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

Cellular Localization

Nuclear

Species Reactivity

EBV

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

50/55kDa doublet

Specificity & Comments

Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Epstein, Alan L.: Immunobiochemical characterization with monoclonal antibodies of Epstein-Barr virus-associated early antigens in chemically induced cells. J. Virology 50:372-379, 1984.

Bioinformatics

NBT00103