2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> CD62L (L-Selectin)

CD62L (L-Selectin)

Mouse Monoclonal Antibody [Clone LAM1-116]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

SDS-PAGE Analysis Purified CD62L Mouse Monoclonal Antibody (LAM1-116). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

A.11; AI528707; CD62 antigen ligand; CD62L; gp90-MEL; IgA nephropathy, susceptibility to, included; L Selectin; L-selectin; LAM1; LECAM1; LEU8; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lnhr; LSEL; Ly-22; LYAM1; Lymph node homing receptor; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; Pln homing receptor; PLNHR; SELL; TQ1

Positive Control

HPBL or Jurkat whole cell lysate.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, Western Blot         More Details

ELISA (For coating, order antibody without BSA)
Flow Cytometry (1-2ug/million cells)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

MAb raised against supernatant from phorbol myristic acid activated human peripheral blood leukocytes.

Cellular Localization

Cytoplasmic.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

65-75kDa

Specificity & Comments

Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Tedder, T.F., et al. 1995. FASEB J. 10: 866-873.
  2. Lasky, L.A. 1995. Ann. Rev. Biochem. 64: 113-139.

Bioinformatics

  •  Entrez Gene ID: 6402
  •  Gene Symbol: SELL
  •  SwissProt: P14151
  •  Chromosome Location: 1q24.2
  •  Unigene: 728756
NBT01587