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Home >> Antibodies >> CD48 (Pan Leukocyte Marker)

CD48 (Pan Leukocyte Marker)

Mouse Monoclonal Antibody [Clone 5-4.8]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified CD48 Mouse Monoclonal Antibody (5-4.8). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

B cell membrane protein; B-cell activation marker; BCM1 surface antigen; BLAST1; Signaling lymphocytic activation molecule 2; SLAM family member 2 (SLAMF2); TCT.1

Positive Control

Daudi, JY, Raji, Jurkat and human lymphocytes. Human lymph node and tonsil.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human peripheral blood lymphocytes

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

45kDa

Specificity & Comments

Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Vaughan HA et al. The isolation of cDNA clones for CD48. Immunogenetics 1991, 33(2):113-117.
  2. Vaughan HA et al. Hu Ly-M3--a human leukocyte antigen. Transplantation 1983, 36(4):446-450.

Bioinformatics

  •  Entrez Gene ID: 962
  •  Gene Symbol: CD48
  •  SwissProt: P09326
  •  Chromosome Location: 1q21.3-q22
  •  Unigene: 243564
NBT01057