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Home >> Antibodies >> CD29 (Stem Cell Marker)

CD29 (Stem Cell Marker)

Mouse Monoclonal Antibody [Clone 12G10]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified CD29 Mouse Monoclonal Antibody (12G10). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Fibrinogen Receptor beta subunit; FNRB; Glycoprotein IIa (GPIIA); Integrin beta-1 (ITGB1); integrin VLA-4 beta subunit; MDF2; MSK12; Very Late Activation Protein beta Polypeptide; VLA-4 subunit beta; VLA-BETA; VLAB

Positive Control

HT1080 whole cell lysate. HeLa cell line.

Known Applications & Suggested Dilutions

ELISA         More Details

ELISA (For coating use Ab at 1-5ug/ml, order Ab without BSA) Optimal dilution for a specific application should be determined.

Immunogen

Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.

Cellular Localization

Cell Surface

Species Reactivity

Human. Does not react with Mouse or Rat.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

110kDa (non-reduced) & 130kDa (reduced)

Specificity & Comments

Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Tamkun, J.W. et al. Cell 46: 271-282 (1986)
  2. Loftus, J.C. et al. Science 249: 915-918 (1990)

Bioinformatics

  •  Entrez Gene ID: 3688
  •  Gene Symbol: ITGB1
  •  SwissProt: P05556
  •  Chromosome Location: 10p11.2
  •  Unigene: 643813
NBT02905