Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CAIX Mouse Monoclonal Antibody (CA9/781).
SDS-PAGE Analysis Purified CAIX Mouse Monoclonal Antibody (CA9/781). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of HCT116 cell lysate CAIX Mouse Monoclonal Antibody (CA9/781).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.