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Home >> Antibodies >> Blood Group Antigen H Type 2 (CD173)

Blood Group Antigen H Type 2 (CD173)

Mouse Monoclonal Antibody [Clone 19-OLE]

Catalog #

Size

20 ug
100 ug
200 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml

Catalog No

Size

20 ug
100 ug
200 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml

Price (USD)

219.00
499.00
499.00
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Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen H Type 2 MAb (19-OLE)

Product Details

Synonyms

A transferase; ABO; B transferase; CD173; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT

Positive Control

KG1 cells or human colorectal carcinoma.

Known Applications & Suggested Dilutions

IF, Immunohistology         More Details

Immunofluorescence (2-4ug/ml)
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Mucinous colonic adenocarcinoma

Cellular Localization

Cell Surface & Cytoplasmic

Species Reactivity

Human. Others-not known.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

Multiple

Specificity & Comments

Recognizes the blood group H type 2 antigens, trisaccharide Fuc1-2Gal1-4GlcNAc1 of human origin. This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.

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200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bioinformatics

  •  Entrez Gene ID: 28
  •  Gene Symbol: ABO
  •  SwissProt: P16442
  •  Chromosome Location: 9q34.2
  •  Unigene: 654423