Home >> Antibodies >> Blood Group Antigen A (CD173)

Blood Group Antigen A (CD173)

Mouse Monoclonal Antibody [Clone HE-193]

Printable

Bioinformatics

Catalog #

Size

20 ug

100 ug

200 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

200 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Price (USD)

219.00

499.00

Printable

Bioinformatics

Product Details

Synonyms

A transferase; ABO; B transferase; CD173; Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; Histo-blood group A transferase; Histo-blood group B transferase; NAGAT

Positive Control

KG1 cells or human colorectal carcinoma tissues.

Known Applications & Suggested Dilutions

IF, Immunohistology More Details

Agglutination
Immunofluorescence (2-4ug/ml)
Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Mixture of erythrocytes of blood group Aand glycoprotein fraction isolated from the saliva of secretors with blood group A

Cellular Localization

Cell Surface

Species Reactivity

Human. Others-not known.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

Multiple

Specificity & Comments

This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.