2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Aldo-keto Reductase Family 1 Member C2 / DD2

Aldo-keto Reductase Family 1 Member C2 / DD2

Mouse Monoclonal Antibody [Clone CPTC-AKR1C2-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

img

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

img

Western Blot Analysis of Human HeLa, K-562 and A431 cell lysates using AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

img

SDS-PAGE Analysis Purified AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1). Confirmation of Purity and Integrity of Antibody.

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using Aldo-keto Reductase Family 1 Member C2 / DD2 Mouse Monoclonal Antibody (CPTC- AKR1C2-1).

Product Details

Synonyms

AKR1C2, 3-alpha-HSD3, AKR1C-pseudo protein, BABP, Dihydrodiol dehydrogenase 2, DD-2, MCDR2, HAKRD, DD, DDH2, HBAB, Pseudo-chlordecone reductase, SRXY8

Positive Control

HeLa, K-562, A431, HepG2, A549 cells. Human liver or stomach tissue.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length AKR1C2 protein

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

37kDa

Specificity & Comments

DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Binstock, J.M., et al. 1992. Res. Commun. 187: 760-766

Bioinformatics

  •  Entrez Gene ID: 1646
  •  Gene Symbol: AKR1C2
  •  SwissProt: P52895
  •  Chromosome Location: 10p15.1
  •  Unigene: 567256
NBT02255