Formalin-fixed, paraffin-embedded Human Adrenal stained with Adipophilin Mouse Monoclonal Antibody (ADFP/1366).
SDS-PAGE Analysis Purified Adipophilin Mouse Monoclonal Antibody (ADFP/1366). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Adipophilin Mouse Monoclonal Antibody (ADFP/1366).
Specificity & Comments
Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.