2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Adipophilin / Perilipin-2 (Marker of Lipid Accumulation)

Adipophilin / Perilipin-2 (Marker of Lipid Accumulation)

Mouse Monoclonal Antibody [Clone ADFP/1366]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded Human Adrenal stained with Adipophilin Mouse Monoclonal Antibody (ADFP/1366).

img

SDS-PAGE Analysis Purified Adipophilin Mouse Monoclonal Antibody (ADFP/1366). Confirmation of Purity and Integrity of Antibody.

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using Adipophilin Mouse Monoclonal Antibody (ADFP/1366).

Product Details

Synonyms

Adipophilin; ADFP; Adipose differentiation-related protein (ADRP); Perilipin-2 (PLIN2)

Positive Control

HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.

Known Applications & Suggested Dilutions

ELISA, IHC-P         More Details

ELISA (For coating, order Ab without BSA)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa 249-376) of human Adipophilin (ADFP) protein (exact sequence is proprietary)

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Others not known.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

48kDa

Specificity & Comments

Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

Related Products


rel_img

PAX8 (Renal Cell Marker)
[clone PAX8/1491]

Applications

WB, IHC

Reactivity

Human

rel_img

Adiponectin (Marker of Obesity)
[clone ADPN/1370]

Applications

WB, IHC

Reactivity

Human

rel_img

AIF1 / Iba1 (Microglia Marker)
[clone AIF1/1909]

Applications

WB, IHC

Reactivity

Human

rel_img

Albumin (Transport Protein)
[clone ALB/2356]

Applications

WB, IHC

Reactivity

Human


200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Kern, P.A., et al. 2004. Perilipin expression in human adipose tissue is elevated with obesity. J. Clin. Endocrinol. Metab. 89: 1352-1358.

Bioinformatics

  •  Entrez Gene ID: 123
  •  Gene Symbol: PLIN2
  •  SwissProt: Q99541
  •  Chromosome Location: 9p22.1
  •  Unigene: 3416
DOC#01366