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Pigment epithelium-derived factor Antibody [BICCN-SERPINF1-2A8]

In Stock
Catalog Number Formulation Size Price
5176-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
5176-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
5176-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Melanosome, Secreted
Gene Name
SERPINF1
Positive Control
Retinal pigment epithelial cells and blood plasma
Immunogen
Recombinant human SERPINF1 protein
Alternate Names
Pigment epithelium-derived factor, EPC-1|OI12|OI6|PEDF|PIG35

Database Links

Entrez Gene ID
5176
SwissProt
P36955

Additional Information

Clone
BICCN-SERPINF1-2A8
Chromosome Location
17p13.3
Mol. Weight of Antigen
46.31kDa
Purification
Protein G

Related Antibodies

View All SERPINF1 Antibodies

Functions

  • Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

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