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Recombinant ETS1 (Marker of Tumor Metastasis) Antibody [ETS1/9828R]

In Stock
Catalog Number Formulation Size Price
2113-RBM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2113-RBM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2113-RBM6-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518)., Acts as a dominant-negative for isoform c-ETS-1A.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cytoplasm, Nucleus
Gene Name
ETS1
Positive Control
Highly expressed within lymphoid cells
Immunogen
Recombinant fragment (around aa226-454) of the human ETS-1 protein (exact sequence is proprietary)
Alternate Names
Protein C-ets-1, ETS-1|EWSR2|c-ets-1|p54

Database Links

Entrez Gene ID
2113
SwissProt
P14921

Additional Information

Clone
ETS1/9828R
Chromosome Location
11q24.3
Mol. Weight of Antigen
50.41kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All ETS1 Antibodies

Functions

  • Transcription factor (PubMed:10698492, PubMed:11909962). Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts (PubMed:20378371). May control the differentiation, survival and proliferation of lymphoid cells (PubMed:20378371). May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion (PubMed:15247905, PubMed:15592518)., Acts as a dominant-negative for isoform c-ETS-1A.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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