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Home >> Antibodies >> JUNB

JUNB

Mouse Monoclonal Antibody [Clone PCRP-JUNB-3G2]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Flow Cytometric Analysis of PFA-fixed HeLa cells. JUNB Mouse Monoclonal Antibody (PCRP-JUNB-3G2) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

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Immunofluorescence Analysis of PFA-HeLa cells. JUNB Mouse Monoclonal Antibody (PCRP-JUNB-3G2) followed by goat anti-mouse IgG-CF488 (green). Phalloidin counterstain (red).

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SDS-PAGE Analysis Purified JUNB Mouse Monoclonal Antibody (PCRP-JUNB-3G2). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using JUNB Mouse Monoclonal Antibody (PCRP-JUNB-3G2).

Product Details

Synonyms

Activator protein 1 (AP1); Transcription factor junB; junB proto oncogene 9

Positive Control

HeLa, K562 or MCF-7 cells.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human JUNB protein

Cellular Localization

Nucleus

Species Reactivity

Human

Host / Ig Isotype

Mouse / IgG1

Mol. Weight of Antigen

39kDa

Specificity & Comments

The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Maki, Y., et al. 1987. Proc. Natl. Acad. Sci. USA 84: 2848-2852.
  2. Nishimura, T., et al. 1988. Oncogene 3: 659-663.

Bioinformatics

  •  Entrez Gene ID: 3726
  •  Gene Symbol: JUNB
  •  SwissProt: P17275
  •  Chromosome Location: 19p13.13
  •  Unigene: 25292