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Home >> Antibodies >> ELK1

ELK1

Mouse Monoclonal Antibody [Clone PCRP-ELK1-1B9]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Analysis of Protein Array containing more than 19,000 full-length human proteins using ELK1 Mouse Monoclonal Antibody (PCRP-ELK1-1B9).

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SDS-PAGE Analysis Purified ELK1 Mouse Monoclonal Antibody (PCRP-ELK1-1B9). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

ETS transcription factor; ELK2 member of ETS oncogene family; ETS domain-containing protein Elk-1; Member of ETS oncogene family; Tyrosine kinase (ELK1) oncogene

Positive Control

HeLa or K562 cells.

Known Applications & Suggested Dilutions

IP         More Details

ELISA
Immunoprecipitation (1-2ug per 100-500ug of total protein (1ml of cell lysate))
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human ELK1 protein

Cellular Localization

Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a

Mol. Weight of Antigen

44.89kDa

Specificity & Comments

Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1 3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Ghysdael, J., et al.1986. Proc. Natl. Acad. Sci. USA 83:1714-1718.
  2. Nucleic Acids Res. 38:D142-D148 (2010).

Bioinformatics

  •  Entrez Gene ID: 2002
  •  Gene Symbol: ELK1
  •  SwissProt: P19419
  •  Chromosome Location: Xp11.23
  •  Unigene: 181128