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Home >> Antibodies >> DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker)

DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker)

Mouse Monoclonal Antibody [Clone DG1/447]

Catalog #

Size

0.5 ml at 100ug/ml

Price (USD)

429.00

Formulation

Purified Ab conjugated to CF488

Catalog No

Size

0.5 ml at 100ug/ml

Formulation

Purified Ab conjugated to CF488

Price (USD)

429.00

Product Details

Synonyms

Anoctamin 1, Calcium Activated Chloride Channel, Discovered On Gastrointestinal Stromal Tumors Protein 1,TAOS2, ORAOV2, TMEM16A

Positive Control

Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood)
Immunofluorescence (1:50-1:100)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human DOG-1 protein

Cellular Localization

Cell Surface and Cytoplasm

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

~114kDa

Specificity & Comments

Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs is nearly identical: 94.4% vs. 94.7%.

Related Products



Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.

Key References

  1. Espinosa I, et. al. Am J Surg Pathol 2008;32:210-218.

Bioinformatics

  •  Entrez Gene ID: 55107
  •  Gene Symbol: TMEM16A
  •  SwissProt: Q5XX6
  •  Chromosome Location: 11q13.3
  •  Unigene: 503074
NBT00447