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Mediator of RNA polymerase II transcription subunit 30 Antibody [PCRP-MED30-1B12]

In Stock
Catalog Number Formulation Size Price
90390-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
90390-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
90390-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Nucleus
Gene Name
MED30
Positive Control
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle
Immunogen
Recombinant human MED30 protein
Alternate Names
Mediator of RNA polymerase II transcription subunit 30, MED30S|THRAP6|TRAP25

Database Links

Entrez Gene ID
90390
SwissProt
Q96HR3

Additional Information

Clone
PCRP-MED30-1B12
Chromosome Location
8q24.11
Mol. Weight of Antigen
20.28kDa
Purification
Protein G

Related Antibodies

View All MED30 Antibodies

Functions

  • Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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