Printable Datasheet

Recombinant FCGR2B Antibody [CD32b13485R]

In Stock
Catalog Number Formulation Size Price
2213-RBM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2213-RBM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2213-RBM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Awaiting product image

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Flow Cytometry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cell membrane
Gene Name
FCGR2B
Positive Control
Is the most broadly distributed Fc-gamma-receptor
Immunogen
Recombinant fragment (around aa 294-3100) of human FCGR2B protein
Alternate Names
Low affinity immunoglobulin gamma Fc region receptor II-b, CD32|CD32B|FCG2|FCGR2|FCGR2C|FcGRIIB|FcRII-c|FcgammaRIIb|IGFR2

Database Links

Entrez Gene ID
2213
SwissProt
P31994

Additional Information

Clone
CD32b13485R
Chromosome Location
1q23.3
Mol. Weight of Antigen
34.04kDa
Purification
Protein G

Related Antibodies

View All FCGR2B Antibodies

Functions

  • Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

NeoBiotechnologies holds Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK
Call Us Now: 1-866-2-NEOBIO (1-866-263-6246)
NeoBiotechnologies Logo
Company Info
Antibodies
Antibody Validation
Research Areas
Resources
Newsletter Signup Updates & Sales