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Nucleus accumbens-associated protein 1 Antibody [PCRP-NACC1-1A1]

In Stock
Catalog Number Formulation Size Price
112939-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
112939-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
112939-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2 / Kappa
Cellular Localization
Cytoplasm, Nucleus
Gene Name
NACC1
Positive Control
Overexpressed in several types of carcinomas including ovarian serous carcinomas
Immunogen
Recombinant full-length human NACC1 protein
Alternate Names
Nucleus accumbens-associated protein 1, BEND8|BTBD14B|BTBD30|NAC-1|NAC1|NECFM

Database Links

Entrez Gene ID
112939
SwissProt
Q96RE7

Additional Information

Clone
PCRP-NACC1-1A1
Chromosome Location
19p13.13
Mol. Weight of Antigen
57.26kDa
Purification
Protein A

Related Antibodies

View All NACC1 Antibodies

Functions

  • Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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