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At NeoBiotechnologies, we proudly offer a diverse portfolio of over a thousand HuProt-validated antibodies [link to HuProt page]. This powerful, high-throughput technology provides information about an antibody’s specificity, binding affinity, and potential cross-reactivity against various target proteins and ensures that your experiments yield reliable and accurate results. Our commitment to specificity and reliability means you can trust our products to deliver precise and consistent outcomes every time.
Immunohistochemistry (IHC) is used in biomedical research and diagnostics to visualize the presence, localization, and distribution of specific proteins or antigens within tissue sections. It involves using antibodies to target and bind to specific proteins in tissue samples. Then, these antibody-protein interactions are detected using various chromogenic or fluorescence methods. IHC is routinely used to evaluate protein expression patterns during the onset and progression of various diseases and cancers [link cancer markers category page].
Monoclonal antibodies target specific molecules or cells in the human body. These antibodies are produced in a laboratory by cloning identical immune cells, allowing for the creation of highly precise and consistent antibodies. Monoclonal antibodies have gained significant attention for their diverse applications since they can be engineered to recognize and bind to a single, predetermined target, such as a disease-causing protein, virus, or cancer cell. This precision makes them invaluable tools for monitoring protein expression in a wide range of diseases, from cancer to autoimmune disorders and infectious diseases.
At NeoBiotechnologies, we create our mouse [link], rabbit [link], and rat [link] monoclonals by hybridoma and recombinant techniques [link to the recombinant page]. All of our monoclonal antibodies are sequenced multiple times, ensuring lot-to-lot consistency. You can also contact us about bulk orders [link] and licensing for diagnostic and/or therapeutic applications [link].
Rabbit Polyclonals
Rabbit polyclonal antibodies are a valuable class of antibodies widely used in scientific research, diagnostics, and various applications. Unlike monoclonal antibodies, polyclonal antibodies are generated by immunizing rabbits with a specific antigen. The immune response in the rabbit results in the production of a diverse pool of antibodies, each capable of binding to different epitopes of the target antigen and enhancing the likelihood of successful detection and increased specificity in assays. Their versatility and broad applicability make them essential tools in advancing scientific understanding, diagnostics, and various laboratory applications.
Recombinant monoclonal antibodies are a cutting-edge class of antibodies engineered through genetic manipulation techniques. These antibodies are generated by cloning specific antibody-producing cells from immunized animals and incorporating their variable complementarity-determining regions (CDRs) into a recombinant expression system, typically mammalian cells or bacteria. These antibodies offer precision targeting, consistency and reproducibility, reduced immunogenicity, customization, and scalability, making them an invaluable tool for research, diagnostics, and therapeutics.
Recombinant monoclonal antibodies are widely used in immunohistochemistry (IHC) experiments to visualize and assess the distribution of specific antigens in tissues, aiding in disease diagnosis and research. These antibodies are also commonly employed in immunoprecipitation assays to isolate specific protein complexes for downstream analysis.
We offer a variety of recombinant mouse [link] and rabbit [link] monoclonals. With our state-of-the-art production capabilities, NeoBiotechnologies can manufacture recombinant antibodies at scale [link to bulk orders], ensuring a steady supply for research and clinical applications. Join us in unlocking the potential of our innovative recombinant antibody solutions.
Transcription factors are proteins that play a pivotal role in gene expression regulation, cell development and differentiation, cell response to signals, and disease mechanisms. They bind to specific DNA sequences, typically in the promoter or enhancer regions of genes, and can either activate or repress the transcription of those genes. Their importance lies in their ability to control when and to what extent genes are transcribed into RNA, ultimately determining the production of specific proteins within a cell.
We have a portfolio of about 1300 transcription factor antibodies developed under an NIH Grant that enable researchers to probe the complex mechanisms that govern gene expression and provide insights that have implications for a wide range of scientific and medical applications.
MonoPoly antibodies (MonoPolys™) are created by combining genetic material from different sources to produce a diverse array of antibodies engineered to target specific antigens. Unlike traditional monoclonal antibodies derived from a single parent cell, MonoPolys are generated from multiple cell lines, allowing these antibodies to simultaneously target multiple epitopes on a single antigen and enhancing their specificity and effectiveness.
These antibodies are crucial tools for diagnostics, as they can accurately detect and quantify specific disease-associated biomarkers. They are also used in therapeutic applications to treat cancer, autoimmune disorders, and infectious diseases. Additionally, the ability to tailor these antibodies for various applications makes them versatile assets in the fields of medicine and research.
NeoBiotechnologies utilizes advanced biotechnological methods to ensure a high degree of precision and control over the antibody production process, leading to consistent quality and reduced batch-to-batch variability.