MMP9 Antibodies

Matrix Metalloproteinase 9 (MMP9) has a molecular weight of approximately 92 kDa. It is expressed in various cell types, including neutrophils, macrophages, fibroblasts, and endothelial cells, and is often induced in response to inflammatory signals. This protein belongs to the family of matrix metalloproteinases, which are involved in the degradation of extracellular matrix components. Its primary function is to cleave and remodel extracellular matrix proteins, particularly gelatin and collagen; thus, it is vital to wound healing, angiogenesis, and immune responses.

MMP9 is implicated in various diseases and pathological conditions, including chronic inflammatory diseases, arthritis, cardiovascular diseases, and cancer. In cancer, it is often associated with tumor invasion, metastasis, and angiogenesis, contributing to the progression of malignancies.

Antibodies against MMP9 are used in research to study its expression levels in cells and tissues. Immunohistochemistry, western blotting, and other techniques employing anti-MMP9 antibodies help researchers analyze its role in physiological and pathological processes. MMP9 is being explored as a potential biomarker for various diseases, including cancer. In diagnostics, measuring Matrix Metalloproteinase 9 levels may provide information about the severity of certain conditions and contribute to prognosis.

Synonyms

Matrix metalloproteinase-9, CLG4B|GELB|MANDP2|MMP-9

Research Areas

Apoptosis, Autophagy, Breast Cancer, Cancer, Cardiovascular, Cell Biology, Cellular Markers and Tags, Developmental Biology, Endocrine, Epigenetics, Gastrointestinal Tract, Hypoxia, Immuno Oncology, Immunology, Kidney, Lymphatic, Metabolism, Microbiology, Muscle, Neuroscience, Pancreatic Cancer, Prostate Cancer, Skin, Stem Cell, AKT Signaling, Angiogenesis, Articular Cartilage Extracellular Matrix, B Cell Markers, Basal Cell Marker, BBB VCAM-1 Signaling, Bladder Cancer, Cardiac Stem Cells, Colon Cancer, Colorectal Cancer, Complement System, CTLA-4 blockade immunotherapy, Cytokine Signaling, Defective Intrinsic Apoptosis, Dendritic Cell Marker, Digestion, Endothelial Cell Marker, Hematopoietic Stem Cells, Immune checkpoint, Infectious Disease, Lipid Metabolism, Lung Cancer, MAPK Signaling, Mast Cell Marker, Melanoma, Mesenchymal Stem Cell Differentiation, Mitochondria Marker, Neural Stem Cells, Neuroinflammation, Nuclear Marker, Oncology, Ovarian Cancer, PD-1 blockade immunotherapy, Signal Transduction, Stem Cell Differentiation, Transcription Factors