Breast Cancer Antibodies

Breast cancer is a multifaceted disease characterized by uncontrolled cell growth in the breast tissue. It encompasses several distinct types, differing in terms of origins and growth patterns. Techniques including Western blots, ELISA, flow cytometry, co-immunoprecipitation, and immunohistochemistry can distinguish among the different types of breast cancer and provide vital information about cell proliferation and disease progression, which is critical for the early detection, prognosis/monitoring, and treatment of the disease.

NeoBiotechnologies is your trusted partner in breast cancer research, offering a comprehensive range of high-quality IHC-validated antibodies targeting breast cancer protein biomarkers (see the table below).

Notable breast cancer biomarkers:

Estrogen Receptor (ER): ER-positive breast cancer is characterized by the presence of estrogen receptors on the cancer cells. ER status is crucial for treatment decisions, as patients with ER-positive tumors may benefit from hormone therapy.
Progesterone Receptor (PR): PR-positive breast cancer indicates the presence of progesterone receptors on the cancer cells. Similar to ER, hormone therapy may be used in the treatment of PR-positive tumors.
Human Epidermal Growth Factor Receptor 2 (HER2): HER2-positive breast cancer has amplification or overexpression of the HER2 gene or protein. HER2 status helps determine treatment options, as targeted therapies like trastuzumab (Herceptin) are used in HER2-positive cases.
Ki-67: a protein associated with cell proliferation. Its measurement can provide information about the growth rate of breast cancer cells, which is essential for prognosis and treatment planning.
p53: a protein involved in regulating cell growth and DNA repair. Mutations in the p53 gene and aberrant expression of the p53 protein are associated with some forms of breast cancer and can affect prognosis and treatment decisions.
Cyclin D1: a protein involved in cell cycle regulation and is often overexpressed in specific breast cancer subtypes, such as luminal breast cancers.
Topoisomerase II (Topo II): an enzyme involved in DNA replication and repair. Its expression can impact the responsiveness of breast cancer to specific chemotherapy agents.
Epidermal Growth Factor Receptor (EGFR): a cell surface receptor that can be overexpressed in some breast cancer subtypes, and its presence may influence treatment decisions. EGFR expression or overexpression is associated with some breast cancer subtypes and may influence treatment options.
Cytokeratins (CK): intermediate filament proteins found in epithelial cells, including breast cancer cells. They are often used in immunohistochemistry to identify and subtype breast cancer cells.
BRCA1 and BRCA2: Mutations in the BRCA1 and BRCA2 genes are associated with an increased risk of hereditary breast cancer. Testing for these mutations can help identify individuals at high risk for breast cancer.
PTEN (Phosphatase and Tensin Homolog): Loss of PTEN expression is associated with some breast cancers and may be related to treatment response and prognosis.

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5

In Stock

Best Seller

p21WAF1 (Tumor Suppressor Protein) Antibody [CIP1/823]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM3

Gene:

CDKN1A

Application:

Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
2

In Stock

p21WAF1 (Tumor Suppressor Protein) Antibody [HJ21]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM4

Gene:

CDKN1A

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry

Reactivity:

Chimpanzee, Human, Monkey, Mouse, Rat

Host:

Mouse

Isotype:

IgG1
3

In Stock

p21WAF1 (Tumor Suppressor Protein) Antibody [SPM306]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM2X

Gene:

CDKN1A

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
3

In Stock

p21WAF1 (Tumor Suppressor Protein) Antibody [DCS-60.2]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM2

Gene:

CDKN1A

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
3

In Stock

p21WAF1 (Tumor Suppressor Protein) Antibody [CIP1/823 + DCS-60.2]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM5

Gene:

CDKN1A

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
2

In Stock

p21WAF1 (Tumor Suppressor Protein) Antibody [AC8]
Price range: $259.00 through $559.00

Catalog Number:

1026-MSM8

Gene:

CDKN1A

Application:

ELISA, Immunofluorescence, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG1
2

In Stock

p53 (Tumor Suppressor Protein) Antibody [TP53/2719]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM19

Gene:

TP53

Application:

Immunohistochemistry

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2b
3

In Stock

p53 (Tumor Suppressor Protein) Antibody [PCRP-TP53-1F7]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM15

Gene:

TP53

Application:

Immunohistochemistry

Reactivity:

Human

Host:

Mouse

Isotype:

IgG1
2

In Stock

p53 Tumor Suppressor Protein Antibody [PAb240]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM7

Gene:

TP53

Application:

ELISA

Reactivity:

Cow, Dog, Hamster, Human, Monkey, Mouse, Rat

Host:

Mouse

Isotype:

IgG1
2

In Stock

p53 Tumor Suppressor Protein Antibody [PAb122]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM4

Gene:

TP53

Application:

ELISA

Reactivity:

Dog, Hamster, Human, Monkey, Mouse, Rat

Host:

Mouse

Isotype:

IgG2b
1

In Stock

p53 Tumor Suppressor Protein Antibody [SPM349]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM7X

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Cow, Dog, Hamster, Human, Monkey, Mouse, Rat

Host:

Mouse

Isotype:

IgG1
3

In Stock

p53 Tumor Suppressor Protein Antibody [TRP/817]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM6

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2b
4

In Stock

p53 Tumor Suppressor Protein Antibody [TRP/816]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM5

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
1

In Stock

p53 Tumor Suppressor Protein Antibody [BP53-12 + DO-7]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM3

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Cow, Human, Monkey

Host:

Mouse

Isotype:

IgG2a, IgG2b
3

In Stock

p53 Tumor Suppressor Protein Antibody [SPM590]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM2X

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Cow, Human, Monkey

Host:

Mouse

Isotype:

IgG2b
3

In Stock

p53 Tumor Suppressor Protein Antibody [SPM589]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM1X

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
3

In Stock

p53 Tumor Suppressor Protein Antibody [PAb1801]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM13

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG1
4

In Stock

p53 Tumor Suppressor Protein Antibody [BP53-12]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM1

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Chicken, Dog, Hamster, Human, Monkey

Host:

Mouse

Isotype:

IgG2a
4

In Stock

p53 Tumor Suppressor Protein Antibody [TP53/1739]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM9

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
4

In Stock

p53 Tumor Suppressor Protein Antibody [DO-1]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM8

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
2

In Stock

p53 Tumor Suppressor Protein Antibody [N/A]
Price range: $259.00 through $559.00

Catalog Number:

7157-RBP11

Gene:

TP53

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Rabbit

Isotype:

IgG
2

In Stock

p53 Tumor Suppressor Protein Antibody [SPM514]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM9X

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2a
5

In Stock

p53 Tumor Suppressor Protein Antibody [DO-7]
Price range: $259.00 through $559.00

Catalog Number:

7157-MSM2

Gene:

TP53

Application:

Immunohistochemistry, Western Blot

Reactivity:

Cow, Human, Monkey

Host:

Mouse

Isotype:

IgG2b
3

In Stock

Phospho C-Jun (Thr91, Thr93) Antibody [C-J 4C4/1]
Price range: $259.00 through $559.00

Catalog Number:

3725-MSM1

Gene:

JUN

Application:

Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity:

Human, Rat

Host:

Mouse

Isotype:

IgG1
4

In Stock

PIK3CD Antibody [PIK3CD/4639]
Price range: $259.00 through $559.00

Catalog Number:

5293-MSM9

Gene:

PIK3CD

Application:

Immunohistochemistry, Western Blot

Reactivity:

Human

Host:

Mouse

Isotype:

IgG2b