Free Shipping in the U.S. for orders over $1000.  Shop Now>>

Printable Datasheet

HIC2 (Hypermethylated in cancer 2) (Transcriptional Repressor) Antibody [PCRP-HIC2-2F8]

In Stock
Catalog Number Formulation Size Price
23119-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$249.00
23119-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$539.00
23119-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$539.00
Flat Rate Domestic: $75 | Orders outside the US - Contact Us for Order Information | Ships next business day
Awaiting product image

Applications & Dilutions

Applications Tested Dillution Protocol Note
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

HIC2 (HIC ZBTB Transcriptional Repressor 2) is a Protein Coding gene. Diseases associated with HIC2 include Orofaciodigital Syndrome X and Simpson-Golabi-Behmel Syndrome, Type 1. HIC2 contains 5 C2H2-type zinc fingers and 1 BTB (POZ) domain. It belongs to the krueppel C2H2-type zinc-finger protein family, Hic subfamily and is a transcriptional repressor. It is a transcription activator of SIRT1.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
ELISA, Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Research Areas
Cardiovascular
Isotype / Light Chain
IgG2b /
Cellular Localization
Nucleus
Gene Name
HIC2
Positive Control
HeLa cells.
Immunogen
Recombinant full-length human HIC2protein
Alternate Names
Hypermethylated in cancer 2 protein, HIC1-related gene on chromosome 22 protein, Hic-3, Zinc finger and BTB domain-containing protein 30, HRG22, KIAA1020, ZBTB30, ZNF907

Database Links

Entrez Gene ID
23119
SwissProt
Q96JB3

Additional Information

Clone
PCRP-HIC2-2F8
Chromosome Location
22q11.21
Mol. Weight of Antigen
66.1kDa

Related Antibodies

View All HIC2 Antibodies

Functions

  • Transcriptional repressor.

Key References

  • Blackshaw S., et al. Nature methods 15.5 (2018 May): 330-338.
  • Song JY, et al. FEBS Lett, 2019 Jul. PMID 31127867

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

Reviews

There are no reviews yet.

Be the first to review “HIC2 (Hypermethylated in cancer 2) (Transcriptional Repressor) Antibody”

Your email address will not be published. Required fields are marked *

PARTNERSHIP OPPORTUNITIES

NeoBiotechnologies holds Exclusive rights to 10,000 recombinant and hybridoma antibody products, available for Licensing or Collaboration.

LETS TALK
Call Us Now: 1-866-2-NEOBIO (1-866-263-6246)
NeoBiotechnologies Logo
Company Info
Antibodies
Antibody Validation
Research Areas
Resources
Newsletter Signup Updates & Sales