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Home >> Antibodies >> FABP5 (Marker of Metastatic Potential in Colorectal Cancer)

FABP5 (Marker of Metastatic Potential in Colorectal Cancer)

Mouse Monoclonal Antibody [Clone CPTC-FABP5-3]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human skeletal muscle stained with FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).

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Formalin-fixed, paraffin-embedded human hepatic carcinoma stained with FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).

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Western blot analysis of HeLa cell lysate using FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).

Product Details

Synonyms

FABP5; E-FABP; EFABP; PA-FABP; PAFABP

Positive Control

MOLT-4, HeLa or HEK-293 cells. Keratinocytes; highly expressed in psoriatic skin.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length FABP5 protein

Cellular Localization

Nuclear. Cytoplasmic.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

15.4kDa

Specificity & Comments

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Liu, Rong-Zong et al. The American Journal of Pathology 178.3 (2011): 997 1008.

Bioinformatics

  •  Entrez Gene ID: 2171
  •  Gene Symbol: FABP5
  •  SwissProt: Q01469
  •  Chromosome Location: 8q21.13
  •  Unigene: 408061