Formalin-fixed, paraffin-embedded human skeletal muscle stained with FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).
Formalin-fixed, paraffin-embedded human hepatic carcinoma stained with FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).
Western blot analysis of HeLa cell lysate using FABP5 Mouse Monoclonal Antibody (CPTC-FABP5-3).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.