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Home >> Antibodies >> CLEC9A / DNGR1 (Dendritic Cell Marker)

CLEC9A / DNGR1 (Dendritic Cell Marker)

Mouse Monoclonal Antibody [Clone 8F9]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified CLEC9A Mouse Monoclonal Antibody (8F9). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

C-type lectin domain family 9 member A (CLEC9A); DNGR1

Positive Control

MCF-7 cells (FACS/IF).

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, IF         More Details

ELISA (For coating, order antibody without BSA)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

27kDa

Specificity & Comments

This MAb recognizes a protein of 27kDa, identified as CLEC9A (C-type lectin domain family 9 member A). Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A, also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor.

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Drickamer, K. 1999. Curr. Opin. Struct. Biol. 9: 585-590.
  2. Huysamen, C., et al. 2008. J. Biol. Chem. 283: 16693-16701

Bioinformatics

  •  Entrez Gene ID: 283420
  •  Gene Symbol: CLEC9A
  •  SwissProt: Q6UXN8
  •  Chromosome Location: 12p13.2
  •  Unigene: 531189
NBT03063