Recombinant GnRH-Receptor / LH-RH Receptor Antibody [rGNRHR/6538]

In Stock
Catalog Number Formulation Size Price
2798-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2798-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2798-MSM5-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

Product Properties & Targets

Host
Mouse
Applications
Species Reactivity
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Cell membrane
Gene Name
Positive Control
Pituitary, ovary, testis, breast and prostate but not in liver and spleen
Immunogen
Recombinant fragment (around aa1-29) of the human GnRH-Receptor (LHRH Receptor) protein (exact sequence is proprietary)
Alternate Names
Gonadotropin-releasing hormone receptor, GNRHR1|GRHR|HH7|LHRHR|LRHR

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
rGNRHR/6538
Chromosome Location
4q13.2
Mol. Weight of Antigen
37.73kDa
Expression System
CHO Cells
Purification
Protein A

Functions

  • Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
PARTNERSHIP OPPORTUNITIES

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