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Human Herpes Virus 8 (HHV8) Antibody [LN53]

Additional information

Catalog Number: RTM1-1746
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
RTM1-1746-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
RTM1-1746-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
RTM1-1746-P1ABX
Purified Ab WITHOUT BSA at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Human Herpes Virus 8 (HHV8) Antibody

SDS-PAGE Analysis of Purified HHV8 Rat Monoclonal Antibody (LN53). Confirmation of Purity and Integrity of Antibody.

  • ELISA
  • IF
  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunofluorescence (IF) 1-3ug/ml
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Rat Monoclonals
Host
Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Species Reactivity
Species Independent
Clone
LN53
Isotype
IgG2c
Light Chain
Kappa
Cellular Localization
N/A
Gene Name
N/A
Positive Control
Kaposi's sarcoma. Cultured cells infected with HHV8.
Immunogen
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • N/A
Key References
  • Dupin et al. Proc. Natl. Acad. Sci. USA 96: 4546, 1999.
  • Ablashi et al. Clinc Microbiol Reviews 15: 439, 2002
  • Kellam et al. J Virol 73: 5149, 1999.
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
Not Applicable
SwissProt
N/A
Chromosome Location
Not Applicable
Mol. Weight of Antigen
Not Known
Alternate Names
N/A, N/A, HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV

Summary

HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.

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