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Recombinant Uroplakin 3A (Bladder Carcinoma Marker) Antibody [UPK3A/13759R]

In Stock
Catalog Number Formulation Size Price
7380-RBM29-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
7380-RBM29-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
7380-RBM29-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Endoplasmic reticulum membrane
Gene Name
UPK3A
Positive Control
Expressed in ureter
Immunogen
Recombinant fragment (around aa240-257) of the human Uroplakin 3A protein (exact sequence is proprietary)
Alternate Names
Uroplakin-3a, UP3A|UPIII|UPIIIA|UPK3

Database Links

Entrez Gene ID
7380
SwissProt
O75631

Additional Information

Clone
UPK3A/13759R
Chromosome Location
22q13.31
Mol. Weight of Antigen
30.67kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All UPK3A Antibodies

Functions

  • Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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