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ZSCAN12 (Transcriptional Corepressor) Antibody [PCRP-ZSCAN12-2B2]

In Stock
HuProt Validated
Catalog Number Formulation Size Price
9753-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
9753-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
9753-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Immunofluorescence (IF)
1-3ug/ml

Summary

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Belonging to the Kruppel C2H2-type zinc-finger protein family, ZFP96 (zinc finger protein 96 homolog), also known as ZSCAN12 (zinc finger and SCAN domain-containing protein 12) and zinc finger protein 305, is a 604 amino acid nuclear protein that contains one SCAN box domain and 11 C2H2-type zinc fingers. ZFP96 is upregulated by 8-fold from day 13 of pregnancy to day 1 post-partum, suggesting that ZFP96 functions as a transcription factor by switching off pro-survival genes and/or upregulating pro-apoptotic genes of the corpus luteum.

Product Properties & Targets

Antibody Type
Host
Mouse
Species Reactivity
Research Areas
Isotype / Light Chain
IgG2b /
Cellular Localization
Nucleus.
Gene Name
Positive Control
HeLa or U87 cells. Ubiquitous tissue expression.
Immunogen
Recombinant fragment (around aa37-132) of human ZSCAN12 protein
Alternate Names
Zinc finger and SCAN domain-containing protein 12, Zinc finger protein 305, Zinc finger protein 96, dJ29K1.2, KIAA0426, ZFP96, ZNF29K1, ZNF305, ZNF96

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
PCRP-ZSCAN12-2B2
Chromosome Location
6p22.1
Mol. Weight of Antigen
70.22kDa

Functions

  • May be involved in transcriptional regulation.

Key References

  • Blackshaw S. Nature methods15.5 (2018 May): 330-338.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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