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Zinc Finger Protein 846 / ZNF846 Antibody [ZNF846/2687]

In Stock
Catalog Number Formulation Size Price
162993-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
162993-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
162993-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF846 may be involved in transcriptional regulation.

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Isotype / Light Chain
IgG2a / Kappa
Cellular Localization
Nucleus
Gene Name
Positive Control
HeLa whole cell lysate. Prostate or breast carcinoma.
Immunogen
Recombinant full-length human ZNF846 protein
Alternate Names
Zinc finger protein 846, zinc finger protein 846

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
ZNF846/2687
Chromosome Location
19p13.2
Mol. Weight of Antigen
60.55kDa

Functions

  • May be involved in transcriptional regulation.

Key References

  • Bennett EJ, Rush J, Gygi SP, Harper JWBennett EJ, et al. Cell, 2010 Dec 10.

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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