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Suprabasin (SBSN) (CALB1) Antibody [SBSN/7964]

Additional information

Catalog Number: 374897-MSM4
Host:

Reactivity:

Gene:

In Stock

Trial Size Available

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In Stock
Catalog Number Formulation Size Price
374897-MSM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
374897-MSM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
374897-MSM4-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Suprabasin (SBSN) (CALB1) Antibody

Formalin-fixed, paraffin-embedded human esophagus stained with Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7964). Inset: PBS instead of primary antibody; secondary only negative control.

Suprabasin (SBSN) (CALB1) Antibody - Image 2

Formalin-fixed, paraffin-embedded human skin stained with Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7964). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Suprabasin (SBSN) (CALB1) Antibody - Image 3

Formalin-fixed, paraffin-embedded human skin stained with Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7964). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Suprabasin (SBSN) (CALB1) Antibody - Image 4

SDS-PAGE Analysis of Purified Suprabasin (SBSN) Mouse Monoclonal Antibody (SBSN/7964). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Clone
SBSN/7964
Isotype
IgG
Cellular Localization
Cytoplasm. Secreted.
Gene Name
SBSN
Positive Control
Human thymus|uterus or esophagus.
Immunogen
Recombinant fragment of human SBSN protein (exact sequence is proprietary)
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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VIEW ALL ANTIBODIES

Other Information

Key References
  • Olsen, A., et al. 1994. Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region. Genomics 23: 659-668.
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
374897
SwissProt
Q6UWP8
Chromosome Location
19q13.12
Mol. Weight of Antigen
61kDa
Alternate Names
Suprabasin, HLAR698; Suprabasin; UNQ698

Summary

Suprabasin (SBSN) is a 247 amino acid secreted protein that is upregulated in differentiating keratinocytes and is though to play a role in epidermal differentiation. Expressed in uterus, skin, thymus and esophagus, suprabasin is encoded by a gene that maps to human chromosome 19q13.12. Chromosome 19 consists of about 63 million bases with over 1,400 genes, making up over 2% of human genomic DNA. Chromosome 19 is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fca receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19.

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