Printable Datasheet

Substance-P receptor Antibody [TACR1/16596]

In Stock
Catalog Number Formulation Size Price
6869-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
6869-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
6869-MSM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG2b /
Cellular Localization
Cell membrane
Gene Name
TACR1
Immunogen
Recombinant fragment (around aa 309-407) of human TACR1 protein
Alternate Names
Substance-P receptor, NK1R|NKIR|SPR|TAC1R

Database Links

Entrez Gene ID
6869
SwissProt
P25103

Additional Information

Clone
TACR1/16596
Chromosome Location
2p12
Mol. Weight of Antigen
46.25kDa
Purification
Protein G

Related Antibodies

View All TACR1 Antibodies

Functions

  • This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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