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Recombinant TSH-Receptor, A-Chain (Thyroid Marker) Antibody [TSHR/17641R]

Additional information

Catalog Number: 7253-RBM23
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
7253-RBM23-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
7253-RBM23-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
7253-RBM23-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant TSH-Receptor, A-Chain (Thyroid Marker) Antibody in SDS-PAGE

Recombinant TSH-Receptor, A-Chain (Thyroid Marker) Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Recombinant TSH-Receptor, A-Chain (Thyroid Marker) Rabbit Monoclonal Antibody (TSHR/17641R). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Clone
TSHR/17641R
Isotype
IgG
Light Chain
Kappa
Cellular Localization
Basolateral cell membrane, Cell membrane
Gene Name
TSHR
Positive Control
Expressed in thyroide cells (at protein level) (PubMed:11847099)
Immunogen
Recombinant full-length human TSHR protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
7253
SwissProt
P16473
Chromosome Location
14q31.1
Mol. Weight of Antigen
86.84kDa
Alternate Names
Thyrotropin receptor, CHNG1|LGR3|hTSHR-I

Summary

Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

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