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Recombinant Syndecan-1 Antibody [SDC1/13289R]

In Stock
Catalog Number Formulation Size Price
6382-RBM17-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
6382-RBM17-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
6382-RBM17-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity).

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Extracellular exosome, Membrane, Secreted
Gene Name
SDC1
Positive Control
Detected in placenta (at protein level) (PubMed:32337544)
Immunogen
Recombinant fragment (around aa1-250) of human CD138 protein
Alternate Names
Syndecan-1, CD138|SDC|SYND1|syndecan

Database Links

Entrez Gene ID
6382
SwissProt
P18827

Additional Information

Clone
SDC1/13289R
Chromosome Location
2p24.1
Mol. Weight of Antigen
32.46kDa
Purification
Protein A

Related Antibodies

View All SDC1 Antibodies

Functions

  • Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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