PARTNERSHIP OPPORTUNITIES
Formalin-fixed, paraffin-embedded human pancreasstained with Laminin Receptor Recombinant Rabbit Monoclonal (RPSA/6332R). Inset: PBS instead of primary antibody; secondary only negative control.
Formalin-fixed, paraffin-embedded human pancreasstained with Laminin Receptor Recombinant Rabbit Monoclonal (RPSA/6332R). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human colonstained with Laminin Receptor Recombinant Rabbit Monoclonal (RPSA/6332R). HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified RPSA Recombinant Rabbit Monoclonal Antibody (RPSA/6332R). Confirmation of Purity and Integrity of Antibody
Western Blot Analysis of Human Pancreas, Human Skin, Human Spleen, Human Stomach, HeLa and 3T3 lysates using Laminin Receptor Recombinant Rabbit Monoclonal Antibody (RPSA/6332R).
Western Blot Analysis of Pancreas, Skin and Spleen tissue lysates of different species using Laminin Receptor Recombinant Rabbit Monoclonal Antibody (RPSA/6332R).
Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
